What are you hanging? Pictures, shelf, drapery? Lots of different answers.
Molly's & toggles are very different animals. Toggles are stronger than molly's, but mollys have distinct advantages when they're enough. Once you assemble & insert a toggle you lose the wing part if you need to take it out. Molly's don't care. You can remove & reinsert the screw all you want. When it's time to patch, toggles leave a bigger hole. The trick to remove Molly's is to start with a small screwdriver & carefully lift the edge of the flat part just enough to grab it with wire cutters (the tool formerly known as dikes) & break that part off. Poke the remaining part through & you have 1/4" hole instead of at least a 1/2" from toggle. The biggest problem with mollys is over tightening. As you tighten a molly, the wings pull up flat against the wall. If you keep going the whole thing collapses into a wad & starts digging into the wall. Try a couple on a scrap piece of s-rock to see. Also, with the bigger molleys (& sometimes even the 1/4" ones) they'll just twist in the hole before they start to pull in. Don't start driving them at full speed on your drill.
I don't remember the name of the strongest hollow wall anchor. It's much newer than the molly or toggle. It's kinda a mash up of a molly, a toggle, & an easy anchor. (Easy anchors look like big funky screws with really coarse threads. More on them later but don't use them.) These anchors drill into the wall using a Phillips bit. The part that snugs against the wall is what looks like the easy anchor. When you keep driving the screw pushes a piece out like a toggle. Keep driving & the screw pulls that piece against the wall. You can take the screw back out, too. This anchor leaves a huge hole.
The max weight for an easy anchor is a thermostat. More on that another time.
Well I need to get ready and go help break down & load a disaster relief field kitchen. We did a demo/promo yesterday as part of an event. With all the devastating weather lately we need more volunteers.
Later...