On the cold side, run as large a pipe as you like to the fixtures. Won't give you any problems.
On a small home with all of the fixtures close to the water heater, it won't matter too much if you run 3/4" to all of the fixtures.
But if you have a bathroom 60' of pipe length away from the water heater, do yourself a huge favor and run 1/2" over to it. It takes a long time to clear out the cold water from a such a long run of pipe, running the hot line in 3/4" will cause it to take roughly twice as long to get hot water to the bathroom, and you will waste more energy as well.
My learned factoid of the day...
Now will the reduced hot supply line cause any volume problems with many faucets installed downstream?