If you know what zone you are working on I would turn off the pump for that zone, shut the yellow handle ball valve by the pump, shut the red handle ball valve on the return, connect a hose to the zone drain, run the hose to a floor drain or outside, drain down the zone, leave zone drain open, make changes, open yellow handle ball valve, let water run through the hose until no more air comes out, open red handle ball valve, if no more air close zone drain, turn on pump, check for proper operation.